Fred Hutch

Clinical Trials Physician/Protocol Team Lead, HVTN and CoVPN

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The HIV Vaccine Trials Network (HVTN) is the world’s largest publicly funded multi-disciplinary international collaboration facilitating the development of vaccines to prevent HIV/AIDS. Most recently, the COVID-19 Prevention Network (CoVPN) was formed by the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health to respond to the global pandemic. Using the infectious disease expertise of their existing research networks and global partners, NIAID has directed the HVTN to utilize their experience and expertise to address the pressing need for vaccines and antibodies against the SARS-CoV-2 virus. The mission of CoVPN is to conduct Phase 3 Efficacy Trials to prevent infection and COVID-19 disease. CoVPN will work to develop and conduct studies to ensure rapid and thorough evaluation of United States government-sponsored COVID-19 vaccines and antibodies for the prevention of COVID-19 disease

The Clinical Trials Physician plays a key role in providing scientific and clinical oversight and project management for the development and implementation of HIV vaccine and monoclonal antibody trials. We are looking for a physician with active interest in early phase trials who will work with the NIH and other developers in translating preclinical to clinical development. Clinical trials physicians report directly to HVTN leadership. Some experience with early phase trials; knowledge of preclinical toxicity models is desirable but not mandatory.


  • In collaboration with Network Principal Investigators and HVTN and CoVPN leadership, provide scientific review and input into concept and protocol development
  • Manage multidisciplinary teams and institutions organized around the development and implementation of HIV and CoVPN vaccine and monoclonal antibody protocols
  • Represent the Network in interactions with Principal Investigators, vaccine developers, and other vaccine research and public health organizations involved in HIV vaccine discovery
  • Contribute to a core capacity for review and summary of scientific literature and analysis related to key issues for trial design.
  • Manage timelines for protocol development and implementation, to assure timely start dates for clinical trials. This includes process development and manufacturing of novel products
  • Participate in the review of safety data from all phases of HIV vaccine and monoclonal antibody clinical trials; this includes providing clinical input into the design of clinical monitoring plans and serving as medical monitor for clinical trials
  • Other duties as assigned


Education and training:

  • A physician (M.D. or equivalent degree) is required
  • Preference will be given to those applicants with experience in clinical trials and to those applicants with training in phase 1 or preclinical evaluations of vaccines or antibodies
  • Board certification in internal medicine, family practice, pediatrics, preventive medicine, or infectious disease is desirable.

The ideal candidate should:

  • be highly organized
  • have exceptional written and verbal communication skills
  • have experience managing multidisciplinary teams
  • be able to handle challenging workloads and multiple concurrent projects
  • be proficient with standard business productivity software, including word processing, spreadsheet, presentation graphics, and database applicants

statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

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